Lazysodium can support any reasonably modern machine with a reasonably modern architecture. As Lazysodium is binding on Libsodium, Lazysodium is constrained by Libsodium's supported CPU architectures which can be found here. Therefore Lazysodium currently supports:
Windows 7 and above.
Ubuntu 14.04 and above*.
Android 16 and above.
iOS 10.2 and above.
MacOS 10.11 and above.
Arm6 and above (e.g. Raspberry Pi 1 and above).
*Support for other linux distros can theoretically be added by cross-compilation, just create a GitHub issue and we'll see what we can do.